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Introducing DryDerm Gel
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Glycopyrrrolate and How it Works
Glycopyrrolate (a.k.a. Robinul) is the principle or active ingredient in DryDerm G wipes. Several clinical studies have shown that it very effective in treating gustatory hyperhidrosis or sweating. But how exactly does it work to achieve these results is a good question. Following is a description of how it does so.
First of all, we need to understand that sweat glands are innervated. In other words, each sweat gland will have tiny nerve endings associated with it. These nerve endings will either be somewhat 'dormant' or will stimulate the sweat gland to produce and secrete sweat. Ultimately, a region in the brain is responsible for sending an 'on or off' signal depending on whether or not there is an increase in body temperature (see Mechanism Behind Sweating page).
While an increase in body temperature is the usual process that triggers the brain to send signals to the sweat gland, in gustatory sweating, that trigger is certain foods. So-called 'culprits foods' fool a specific region of the brain to send 'ON' signals to the sweat glands found in the facial region.
And so, glycopyrrolate blocks that part of the nerve signal that stimulates the sweat glands to produce sweat. Nerve signals are transmitted from nerve to nerve or from nerve to end-organ (e.g. sweat glands) via the release of neurotransmitters. Glycopyrrolate blocks the release of the neurotransmitters and as a result, the signal becomes attenuated. A dimished or lack of signal results in a reduction in the production and secretion of sweat.
DryDerm G facial wipes.
For gustatory sweating and
excessive sweating of the facial region.
Available in 1% and 2% strengths